한빛사 논문
Abstract
Nohyun Lee and Taeghwan Hyeon *
World Class University Program of Chemical Convergence for Energy & Environment, and School of Chemical and Biological Engineering, Seoul National University, Seoul, 151-744, Korea.
† Part of the nanomedicine themed issue.
Various magnetic nanoparticles have been extensively investigated as novel magnetic resonance imaging (MRI) contrast agents owing to their unique characteristics, including efficient contrast effects, biocompatibility, and versatile surface functionalization capability. Nanoparticles with high relaxivity are very desirable because they would increase the accuracy of MRI. Recent progress in nanotechnology enables fine control of the size, crystal structure, and surface properties of iron oxide nanoparticles. In this tutorial review, we discuss how MRI contrast effects can be improved by controlling the size, composition, doping, assembly, and surface properties of iron-oxide-based nanoparticles.
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