한빛사 논문
기초과학연구원, 서울대학교
Taegyu Kanga,b,1, Young Geon Kima,b,1, Dokyoon Kimc,*, Taeghwan Hyeona,b,*
aCenter for Nanoparticle Research, Institute for Basic Science (IBS), Seoul 08826, Republic of Korea
bSchool of Chemical and Biological Engineering, and Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea
cDepartment of Bionano Engineering and Bionanotechnology, Hanyang University, Ansan 15588, Republic of Korea
1These authors contributed equally to this work.
*Corresponding author
Abstract
Spurred by the recent advances in the chemical synthesis of nanomaterials, a group of inorganic nanoparticles with enzyme-mimetic activities has emerged as a new candidate to lead the future of nanomedicine. These so-called nanozymes have several advantages over their natural counterparts, such as more robust catalytic activities over wide ranges of pH and temperature, more economical production cost, and higher design flexibility through the integration and modification of various functional molecules and nanomaterials. To help readers understand this rapidly expanding field, we herein provide a short overview of the enzyme-mimetic activities of inorganic nanoparticles and their applications, with an emphasis on ceria and iron oxide nanoparticles, two of the most widely used nanozymes. Properties of other inorganic nanoparticle-based nanozymes are also briefly summarized. Finally, their current limitations and future outlook are discussed.
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