한빛사 논문
서울대학교
Soo Lim, MD1,2, Jung Hee Kim, MD1, Ji Won Yoon, MD1,2, Seon Mee Kang, MD1,2, Sung Hee Choi, MD1,2, Young Joo Park, MD1,2, Ki Woong Kim, MD3, Jae Young Lim, MD4, Kyong Soo Park, MD, PHD1 and Hak Chul Jang, MD, PHD1,2
1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea;
2Department of Internal Medicine, Seoul National University, Bundang Hospital, Seongnam, Korea;
3Department of Neuropsychiatry, Seoul National University, Bundang Hospital, Seongman, Korea;
4Department of Rehabilitation Medicine, Seoul National University, Bundang Hospital, Seongnam, Korea.
Corresponding author: Hak Chul Jang
Abstract
OBJECTIVE We investigated the prevalence of sarcopenic obesity (SO) and its relationship with metabolic syndrome in a community-based elderly cohort in Korea.
RESEARCH DESIGN AND METHODS In this study, 287 men and 278 women aged 65 or older were recruited. Sarcopenia was defined as the appendicular skeletal muscle mass (ASM) divided by height squared (Ht2) (kg/m2) or by weight (Wt) (%) of <1 SD below the sex-specific mean for young adults. Obesity was defined as a visceral fat area ≥100 cm2.
RESULTS The prevalence of SO was 16.7% in men and 5.7% in women with sarcopenia defined by ASM/Ht2; however, it was 35.1% in men and 48.1% in women by ASM/Wt. Using ASM/Wt, the homeostasis model assessment of insulin resistance of subjects with SO was higher and they were at higher risk for metabolic syndrome (odds ratio [OR] 8.28 [95% CI 4.45–15.40]) than the obese (5.51 [2.81–10.80]) or sarcopenic group (2.64 [1.08–6.44]).
CONCLUSIONS SO defined by ASM/Wt was more closely associated with metabolic syndrome than either sarcopenia or obesity alone.
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