한빛사 논문
Kisong Kim 1, Kyuyeon Cho 1, Junmin Song 2, Masoud Rahmati 3, Ai Koyanagi 4,5, Seung Won Lee 6, Dong Keon Yon 7,8, Jae Il Shin 9, Lee Smith 10
1Yonsei University College of Medicine, Seoul, Republic of Korea.
2Keimyung University School of Medicine, Daegu, Republic of Korea.
3Department of Physical Education and Sport Sciences, Faculty of Literature and Human Sciences, Lorestan University, Khorramabad, Iran.
4Parc Sanitari Sant Joan de Deu/CIBERSAM, ISCIII, Universitat de Barcelona, Fundacio Sant Joan de Deu, Sant Boi de Llobregat, Barcelona, Spain.
5ICREA (Catalan Institution for Research and Advanced Studies), Barcelona, Spain.
6Department of Precision Medicine, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea.
7Center for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, Seoul, Republic of Korea.
8Department of Pediatrics, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, Republic of Korea.
9Department of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea.
10Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Kisong Kim and Kyuyeon Cho are contributed equally to this study as co-first authors.
CORRESPONDING AUTHOR : Jae Il Shin
Abstract
As coronavirus variants are constantly occurring, we tried to understand more about the omicron and delta variants that have hit the world. We provided dynamic information on the case fatality rate (CFR) of the Omicron variant over time and to compare it with that of the Delta variant through meta-analysis. Twenty-four countries were selected by submission counts, submission dates, and confirmed cases. We defined the Delta or the Omicron epidemic period for individual countries as when each variant is over 90%. We further analyzed the Omicron period by dividing it into the initial plateau, increasing, and decreasing phases according to the number of newly confirmed daily cases. Finally, the meta-analysis examined the summary and between-study heterogeneity. The CFR of COVID-19 during the Omicron epidemic was lower than that during the Delta epidemic (odds ratio [OR]: 0.252, 95% confidence interval [CI] 0.205−0.309). The CFR of COVID-19 during the initial plateau phase of Omicron was higher than during other phases. (OR: 1.962, 95% CI 1.607−2.397). The CFR of COVID-19 during the increasing phase was lower than during the decreasing phases (OR: 0.412, 95% CI 0.342–0.498). The Omicron variant had lower CFR compared to the Delta variant, and the initial plateau phase had higher CFR compared to the noninitial phases. These results can help establish global health policies for COVID-19 in the future.
논문정보
관련 링크
연구자 키워드
연구자 ID
관련분야 연구자보기
소속기관 논문보기
관련분야 논문보기
해당논문 저자보기