This paper firstly demonstrated the avian-specific features of zygotic genome activation. Activating genes inside the zygote so that they can take control of development is known as zygotic genome activation. Despite the fact that birds are often used to study how embryos develop, zygotic genome activation in birds is not well understood. Fertilization in birds, including chickens, is different to mammals in that it requires multiple sperm to fertilize an egg cell. As such, zygotic genome activation in birds is likely to differ from that in mammals. In this paper, there are two stages of zygotic genome activation in chickens. The genes derived from the mother become active in the first stage, while genes from the father become active in the second stage. Genome activation in birds is therefore very different to the same process in mammals, which involves genome activation of both parents from the first stage. This extra level of control may help to prevent genetic complications resulting from the presence of multiple sperm, each of which carries a different set of genes from the father.

추천자 - Deivendran Rengaraj (서울대학교)

(한빛사 추천논문에서 가져온 정보입니다.)

 

#aves

 

#chicken

 

#developmental biology